Zyflamend is a proprietary formulation containing ten different herbs and is promoted as having COX-1 and COX-2 inhibition. California poppy is an analgesic and mild sedative (hypnotic) herb. Boswellia has been shown to decrease polymorphonuclear leukocyte infiltration and migration as well as act on different targets of osteoarthritis and rheumatoid arthritis.
You can certainly benefit from combining an anti-inflammatory product with an analgesic product. Therefore, the combination of Zyflamend and California poppy or Boswellia and California poppy could provide you with added benefits. In the case of California poppy, try to take this at night because of the potential drowsiness.
I would recommend that you first try Boswellia or Zyflamend. Continue with the product you selected if you begin to see benefits within the first 2 weeks. It may take up to 1 month before you obtain maximal benefits. You will also be able to see the benefit provided by the nightly use of California poppy.
Before combining the Boswellia and Zyflamend, I recommend that you consult a health care practitioner. In some cases, two anti-inflammatory formulations can be combined and will provide additive benefits. What you have to be careful of is combining ingredients that inhibit or act on the same targets in your body. If the doses of each are high, or the combined effect on the target is too strong, you can end up with side effects. Therefore, it is advisable to consult a health care practitioner to ensure that the products you will combine will provide additive benefits and not cause harm.
One caution, Zyflamend has many ingredients. You should talk to a health care practitioner prior to use if you are taking any medications. In fact, when taking medications it is recommended to talk to a health care practitioner to ensure that there will not be any negative effects (i.e., interactions) from combining drugs and herbs.
Response by Guy Chamberland M.Sc., Ph.D.